A manuscript derived from the Evidence-based Practice Center Program (EPC) systematic review on Cannabis and Other Plant-Based Treatments for Chronic Pain and published in the Annals of Internal Medicine has been selected as one of the "Best of Annals 2022". The report concluded that oral, synthetic cannabis products with high THC and sublingual and some extracted cannabis products may be associated with short-term improvements in chronic pain and increased risk for dizziness and sedation. The EPC report is being continuously updated and maintained as a “living review.”