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AHRQ--Agency for Healthcare Research and Quality: Advancing Excellence in Health Care

Topic Suggestion Description

View Topic Suggestion Disposition (PDF) 1.2 MB

Date submitted: June 20, 2013

Briefly describe a specific question, or set of related questions, about a health care test or treatment that this program should consider.
Does creatine monohydrate increase DHT or estradiol and is it a potential risk factor for hair loss.


Describe why this topic is important.
A lot of people supplement with creatine. It is also found in meat. Hair loss is a global problem.

DHT is a large factor of hair loss. I've seen studies that suggest DHT increases body hair, acne, aggression and libido.

I've also seen a study where DHT up-regulated the gene expression of hypocretin, and pro-melanin-concentrating hormone. This would affect feeding behavior, mood, sleep-wake cycle and energy balance.

Potential Impact

How will an answer to your research question be used or help inform decisions for you or your group?
The results will establish whether creatine affects hair loss and what impact it has on DHT.

Nominator Information

Other Information About You: (optional)
Please choose a description that best describes your role or perspective: (you may select more than one category if appropriate)
Creatine Consumer
If you are you making a suggestion on behalf of an organization, please state the name of the organization
Please tell us how you heard about the Effective Health Care Program