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Read Suggested Topics for Research

Browse or use the search box below to see suggestions submitted by others. Click on the text link to read the full suggestion. Suggestions are presented as they were submitted and are not edited. See Search for Guides, Reviews, and Reports for research in progress and final reports.

Suggestions that have completed the Program's selection process are identified by a topic suggestion disposition (PDF). Suggestions submitted prior to 2008 were reviewed under a different process and disposition reports may not be available.


May 17, 2010

For ST segment elevation patients undergoing PCI -percutaneous coronary intervention, what is the best combination with regard to anticoagulation, device and approach to reduce mortality and length of ...

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May 11, 2010

The Obesity Action Coalition is interested in an investigation of the comparative effectiveness of treatments for obesity including: 1. What is the comparative effectiveness of bariatric surgery (gas ...

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May 10, 2010

Question: What is the etiology of cryptorchidism? What are the environmental factors (maternal smoking, maternal diabetes mellitus etc.) that may contribute to the development of this condition? Qu ...

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May 3, 2010

Do "evidence-based" cancer screening recommendations that do not consider racial/ethnic variation in disease patterns contibute to to the more advanced disease stage at diagnosis and higher mortality ...

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May 3, 2010

In terms of fixing depression what is the difference between cognitive behavioral therapy, medication and Subconscious Restructuring® in terms of measurable documented effectiveness?

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Apr. 29, 2010

I want to suggest that people who have the medical aid should use the government hospital. I feel that the government should support its family first before out sourcin. I do not know in other State b ...

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Apr. 22, 2010

Women before 50 with column surgery & without using hormones., osteopenia & scoleosis

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Apr. 21, 2010

There is no standard for care pertaining to chronic wounds and ischemic or diabetic ulcers on the extremities of patients. What is the comparative effectiveness of treating patient’s, including pat ...

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Apr. 19, 2010

For treatment of osteoarthritis, consider a rheumatoid arthritis drug; compare the effectiveness to see if it would work better than the ordinary osteoarthritis drug; since osteoarthritis is similar i ...

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Apr. 19, 2010

For people with seasonal allergies, what are the best treatment options? Please consider effectiveness, ease of use, side effects, cost & effects on pregnancy

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Apr. 14, 2010

Regarding the amount of cardiac rhythm device´s recalls, FDA warning letters to manufactures and Product Performance Report information (based on Advamed guide) available, it would be interesting to d ...

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Apr. 11, 2010

The persistent rate of new HIV infections is the major obstacle to reducing the morbidity and mortality due to HIV in the United States. Screening for HIV in asymptomatic individuals has many potentia ...

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Apr. 9, 2010

Invention and coding of data analysis methods generally useful for making valid claims from large observational data sets.

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Mar. 20, 2010

Is transradial access comparable to transfemoral access with respect to efficacy and superior with respect of safety in primary percutaneous coronary intervention in ST-elevation myocardial infarction ...

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Mar. 19, 2010

Whether Epidural use to contain the labor pay would result in women's memory loss over a longer-term period

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Mar. 9, 2010

Autism Speaks submitted a nomination on treatments for autism spectrum disorders and it was forwarded to an EPC who was refining a related topic nomination. Three primary areas of the Autism Speaks ...

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Feb. 17, 2010

For patients with mobility limitations but who have trunk stability and upper body strength, what is the comparative risk and benefits of adopting a self-managed bedside commode system versus older as ...

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Feb. 13, 2010

adenomatous polyposis coli have a key role on brain synaptogenesis, neurons.axons,dendrites formation,and several others function.Mutation of that gene causes brain lesion or even toumors on gardner's ...

Feb. 11, 2010

For hospital acquired infections, how can we greatly reduce hospital bacterial contamination and acquired infections by breaking the chain of infection? Can we proactively prevent source viral, biolo ...

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Feb. 8, 2010

Many physicians will state "Pulmonary Hypertension" as the nature of a patient's illness with the underlying meaning of "Right-sided Heart involvement". What is the comparative risks associated with t ...

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Feb. 3, 2010

For clients diagnosed with HF what is the latest evidence based care proptocol for collaborative management of HF clients transitioning from acute care setting to home health care?

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Feb. 3, 2010

For women who have pap exams, what is the effectivenes of the various testing techniques to diagnose precancerous or cancerous cervical lesions?

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Jan. 25, 2010

Treating Adult Obesity - Which specific dietary strategies (with and without medication), behavioral treatment approaches, and physical activity approaches work? In a direct comparison, which is m ...

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Jan. 21, 2010

Screening and Behavioral Counseling Interventions in Primary Care to Reduce Alcohol Misuse Is there direct evidence that the combination of screening and behavioral counseling interventions for alc ...

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Jan. 21, 2010

For asymptomatic adults (excludes HIV-positive persons, transplant recipients and patients with renal failure) and asymptomatic pregnant women: Does screening for hepatitis C virus (HCV) infection ...

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