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Read Suggested Topics for Research

Browse or use the search box below to see suggestions submitted by others. Click on the text link to read the full suggestion. Suggestions are presented as they were submitted and are not edited. See Search for Guides, Reviews, and Reports for research in progress and final reports.

Suggestions that have completed the Program's selection process are identified by a topic suggestion disposition (PDF). Suggestions submitted prior to 2008 were reviewed under a different process and disposition reports may not be available.

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Nov. 8, 2010

? For women in the postpartum period, what is the effectiveness and safety of screening and treatment for depression? Please use the USPSTF framework, which considers not only screening but follo ...

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View Topic Suggestion Disposition (PDF) 128 kB

View Topic Suggestion Disposition (PDF) 128 kB

Nov. 8, 2010

Mindfulness meditation encompasses a range of meditation techniques that have been increasingly used to treat behavioral disorders, especially those associated with stress. Some of these were previous ...

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View Topic Suggestion Disposition (PDF) 146 kB

Nov. 5, 2010

Severe muscle cramps in the legs and feet with severe burning sinsation which may not be related to B-12 deficiency.

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Oct. 28, 2010

For persons with PTSD (and those exposed to traumatic event/s as defined by DSM-IV-TR or ICD-10), what is the comparative effectiveness of different psychotherapy modalities/psychological treatments? ...

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View Topic Suggestion Disposition (PDF) 146 kB

View Topic Suggestion Disposition (PDF) 146 kB

Oct. 21, 2010

Is there a relationship or correlation between vitamin D deficiency and autism?

View Topic Suggestion Disposition (PDF) 119 kB

Oct. 15, 2010

SKIN LESIONS - (Body is partly to completely cover with lesions). Causes & Conditions: Prurigo Nodularis, Lesions, Rashes, Pruritus, Staphlococcus, MRSA's, Dermatitis. Etc...

View Topic Suggestion Disposition (PDF) 122 kB

Oct. 15, 2010

Genetic causes of diabetes

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Oct. 15, 2010

This survey would about early warning signs of multiple sclerosis which I documented as late as 2 years before my diagnosis and early as childhood, I am almost finished with a survey. I spent 10 years ...

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View Topic Suggestion Disposition (PDF) 53 kB

Sept. 22, 2010

For pregnant women, or women recieving preconception care, with depression what are the comparative harms or benefits for both fetus/infant and the mother of continuing treatment with anti-depressants ...

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View Topic Suggestion Disposition (PDF) 43 kB

Sept. 22, 2010

a. For patients undergoing elective colon and rectal surgery, what is the role of oral mechanical bowel preparation? b. It has been “historically proven” that mechanical bowel preparation is necess ...

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Sept. 22, 2010

Women with postpartum depression or women who have had a hysterectamy should NOT take an antidepressant to treat PPD but should take ESTROGEN.

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Sept. 22, 2010

For patients with insomnia, how do commonly used medications compare for effectiveness and harms, including addictive potential.

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View Topic Suggestion Disposition (PDF) 126 kB

Sept. 22, 2010

Evidence-based treatment for pressure ulcers by stage

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View Topic Suggestion Disposition (PDF) 126 kB

View Topic Suggestion Disposition (PDF) 126 kB

Aug. 11, 2010

For elderly patients with sleep apnea and insomnia, what is the comparative effectiveness of improving CPAP compliance using a sedative hypnotic (zolpidem) compared to cognitive-behavioral therapy?

View Topic Suggestion Disposition (PDF) 126 kB

Aug. 11, 2010

KQ 1 - What is the burden and incidence of childhood developmental disabilities (Hearing Loss, Kernicterus/Jaundice, intellectual disability and visual impairment ) in the US? KQ 2 - When is screen ...

View Topic Suggestion Disposition (PDF) 126 kB

Aug. 9, 2010

Survivor of septic shock,ARDS,fungal infection, organ failure, on 12/19/2008 told zero % chance of survival.

View Topic Suggestion Disposition (PDF) 123 kB

Aug. 6, 2010

For patients with trauma (obstetric and non-obstetric) sustained during pregnancy, what is the comparative effectiveness of diagnostic interventions for rapid assessment of trauma to improve materna ...

View Topic Suggestion Disposition (PDF) 129 kB

Aug. 6, 2010

Identification of Comparative Effectiveness Research Review Topics For Common Gynecological Conditions.

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Aug. 6, 2010

For women with low-risk pregnancy status, what is the comparative effectiveness of continuous electronic fetal heart rate monitoring versus alternative monitoring to prevent neonatal morbidity and mor ...

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Aug. 5, 2010

For a patient with thyroid disease, What happens if you are given 84 (20) mg. tablets of prednisone for an allergic reaction and it has caused excruitiating and chronic illnesses to the point ...

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Aug. 5, 2010

For adult patients with a variety of advanced cancers (e.g. non-small-cell lung cancer, bladder cancer, breast cancer, and ovarian cancer) what are the comparative risks and benefits of using maintena ...

Aug. 5, 2010

For venous thromboembolism (VTE) prophylaxis of high risk hospitalized medical patients, a randomized controlled non-inferiority clinical trial should be undertaken to compare standard anticoagulant t ...

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Aug. 4, 2010

Test three cost-free measures (x, y, z) and their effect on a given population (p, q, or r) comparing against control groups, by measuring five objective factors (a, b, c, d, and e). x = water cons ...

View Topic Suggestion Disposition (PDF) 121 kB

Aug. 4, 2010

Is a life style change approach to patients/individuals with degenerative joint disease more effective than the traditional standard of care?

View Topic Suggestion Disposition (PDF) 191 kB

Aug. 4, 2010

Can screening and survellance for colorectal cancer (CRC) using fecal DNA analysis improve health outcomes?

View Topic Suggestion Disposition (PDF) 161 kB

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