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Read Suggested Topics for Research

Browse or use the search box below to see suggestions submitted by others. Click on the text link to read the full suggestion. Suggestions are presented as they were submitted and are not edited. See Search for Guides, Reviews, and Reports for research in progress and final reports.

Suggestions that have completed the Program's selection process are identified by a topic suggestion disposition (PDF). Suggestions submitted prior to 2008 were reviewed under a different process and disposition reports may not be available.

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July 1, 2011

Do Certified Nurse Midwives decrease risk and improve outcomes to pregnant women?

View Topic Suggestion Disposition (PDF) 47 kB

June 8, 2011

Management of obesity in primary care Evidence Question #1 What is the evidence that pharmacotherapy is effective in weight loss and maintenance of weight loss? Evidence Question #2 Are certain ag ...

View Topic Suggestion Disposition (PDF) 67 kB

June 7, 2011

QUESTION: For children and adults with cerebral palsy what is the comparative effectiveness of outcomes for each GMFCS level? BACKGROUND: The Gross Motor Function Classification System for Cerebral ...

View Topic Suggestion Disposition (PDF) 127 kB

June 1, 2011

For patients with colon cancer, what is the comparative effectiveness of multi-parameter gene expression assays (e.g., Oncotype DX® colon cancer test*) versus standard clinical and pathological risk f ...

View Topic Suggestion Disposition (PDF) 133 kB

June 1, 2011

For patients with breast, colorectal, and lung cancers, what is the comparative effectiveness for improving net health outcome of more versus less frequent follow-up imaging to monitor for recurrence ...

View Topic Suggestion Disposition (PDF) 140 kB

June 1, 2011

For patients with ovarian cancer, what is the comparative effectiveness of surveillance using serum cancer antigen 125 (CA 125) versus standard methods (based on clinical symptoms or signs of disease) ...

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June 1, 2011

For patients with advanced or metastatic solid tumors such as non-small cell lung cancer, what is the comparative effectiveness of usual care plus interdisciplinary palliative care versus usual care a ...

View Topic Suggestion Disposition (PDF) 129 kB

June 1, 2011

For patients with early stage breast cancer, what is the comparative effectiveness of alternative methods for post-lumpectomy radiation therapy (whole-breast vs. partial breast; accelerated vs. conven ...

View Topic Suggestion Disposition (PDF) 60 kB

June 1, 2011

What is the comparative effectiveness of using versus not using clinical decision support tools to select immediate treatment versus observation and improve net health outcomes for patients with prema ...

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June 1, 2011

What is the comparative effectiveness of different models of survivorship care and sets of services on late and long-term net health outcomes (e.g., for breast cancer)?

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View Topic Suggestion Disposition (PDF) 129 kB

June 1, 2011

For cancer patients, what is the comparative effectiveness of different strategies to manage the symptoms of chemotherapy for improving net health outcome?

View Topic Suggestion Disposition (PDF) 153 kB

June 1, 2011

For patients with rectal cancer, what is the comparative effectiveness of neoadjuvant (preoperative) radiation therapy plus surgery versus surgery alone to reduce risk of local recurrence and improve ...

View Topic Suggestion Disposition (PDF) 49 kB

June 1, 2011

For patients with rectal cancer, what is the comparative effectiveness of different imaging modalities, alone or in combination (i.e., incremental benefit from using more than one modality) for preope ...

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View Topic Suggestion Disposition (PDF) 48 kB

May 28, 2011

The first wave of children with autism since rates started to skyrocket are beginning to exit the school system yet no one has studied what we can learn from this group (many of whom did not have inte ...

View Topic Suggestion Disposition (PDF) 134 kB

May 10, 2011

For children and young adults with T-cell immunophenotype acute lymphoblastic leukemia (ALL) does the administration of prophylactic cranial irradiation improve event-free and over-all survival.

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May 3, 2011

Benefits and harms associated with cardiopulmonary resuscitation in patients with advanced cancers

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Apr. 22, 2011

1. What is the etiology of acute and chronic urinary retention in adults? 2. How do we define urinary retention (base case) including those with known neurologic problems? (aka What is considered a ...

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View Topic Suggestion Disposition (PDF) 129 kB

Apr. 19, 2011

for people with post surgical (total thyroidectomy) hypothyroidism what is the comparative effectiveness of medications used for TSH (T4) control when there are problems keeping the TSH level within r ...

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Apr. 12, 2011

Trigeminal Neuralgia is a devastating problem that often ends in suicide. The best treatment at this time is the drug Felbamate which can cause Kidney failure in as little as two weeks in most patient ...

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Apr. 5, 2011

• Does the availability of telemedicine services improve access to subspecialty care and address disparities in care for children who live in rural or underserved areas? • How can telemedicine servic ...

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Apr. 4, 2011

For pediatric patients with community acquired pneumonia admitted to the hospital what is the best antibiotic regiment?

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Mar. 31, 2011

Effectiveness of pain management in arachnoiditis. TENS, Ultram, Neurontin, etc

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Mar. 31, 2011

For pregnant woman and women with infants, how accurate is information on the subject of (benefits, ease of initiating, continuing) breastfeeding ? information than others?

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Mar. 31, 2011

What are the comparative side effects of antidepressant medication side effects on low socio-economic ethnic/racial minority adolescents versus white low socio-economic adolescents?

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Mar. 26, 2011

teen pregnancy

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