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Department of Health and Human Services

Read Suggested Topics for Research

Browse or use the search box below to see suggestions submitted by others. Click on the text link to read the full suggestion. Suggestions are presented as they were submitted and are not edited. See Search for Guides, Reviews, and Reports for research in progress and final reports.

Suggestions that have completed the Program's selection process are identified by a topic suggestion disposition (PDF). Suggestions submitted prior to 2008 were reviewed under a different process and disposition reports may not be available.


Oct. 4, 2011

i take diltiazem for my a fib. i am allegic to warfarin. i have found nattokinase (cardiokinase) from to really work fantastic for me- no danger of clots. my doctor and i am a ...

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Sept. 24, 2011

Reproductive health among urban slump

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Sept. 9, 2011

Comparative effectiveness of ultrasound, conventional computed tomography (CT), multidetector computed tomography (MDCT), magnetic resonance imaging (MRI) (using conventional VS novel contrast agents) ...

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Sept. 9, 2011

What is the comparative effectiveness of imaging techniques (e.g. CT scans versus chest X-rays) for monitoring of solitary lung nodules?

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Sept. 9, 2011

What is the effectiveness of the use of pharmacological interventions (FDA approved) in treating alcohol-use disorders in primary care settings?

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Sept. 8, 2011

In view of the latest Affordable Care & Health Reform legislation, how will keeping weak national and individual state-by-state lack of full recognition for autonomous practice in primary care for “no ...

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Sept. 7, 2011

Women are disproportionately affected with thyroid disorders. When I was diagnosed with moderate hyperthyroidism of the Graves' type, I was told that only surgery to remove my entire gland or radioabl ...

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Aug. 23, 2011

For patients with Narcolepsy and sleep paralysis, is there an effective treatment that wont have bad side effects?

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Aug. 15, 2011

treatment that this program shold consider&health care test

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Aug. 15, 2011

For patients with common variable immune deficiency receiving intravenous immunoglobulin therapy (IVIG), what is the difference in long term outcomes for those who receive treatment in their homes vs. ...

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Aug. 4, 2011

In order to prevent the 350,000 annual sudden cardiac deaths a year in the USA and the 21% of unnecessary implanted defibrillator patients why is Cambridge Hearts Microvolt T-Wave Alternans Test a gui ...

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July 27, 2011

In patients with cerebral palsy (CP) and difficulties with feeding, what is the effectiveness of of anti-reflux procedure (since often done in conjunction with gastrostomy placement) or type of tube ...

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July 26, 2011

For Rehab patients, what is the comparative effectiveness of a coordinated primary health care team following the patient with the usual care of hospitalization to home health>

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July 22, 2011

•How effective is Balneotherapy—the therapeutic use of mineral and thermal waters -- for improving the mobility of patients suffering from chronic diseases such as rheumatoid arthritis, fibromyalgia, ...

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July 13, 2011

Percentage of microscopic validation of acute inflammation among appendices removed for acute abdominal pain?

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July 6, 2011

Do patients with chronic illness have better overall outcomes and lower cost of care when they are managed by a specialized care manager? Do patients with cancer have a better overall outcome, improv ...

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July 6, 2011

In patients undergoing IVC Filter Placement what is the indication comparison amongst different ethnicities

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July 5, 2011

For patients who do not have a spleen, what are some of the ways they can help prevent infections.

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July 1, 2011

Do Certified Nurse Midwives decrease risk and improve outcomes to pregnant women?

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June 8, 2011

Management of obesity in primary care Evidence Question #1 What is the evidence that pharmacotherapy is effective in weight loss and maintenance of weight loss? Evidence Question #2 Are certain ag ...

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June 7, 2011

QUESTION: For children and adults with cerebral palsy what is the comparative effectiveness of outcomes for each GMFCS level? BACKGROUND: The Gross Motor Function Classification System for Cerebral ...

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June 1, 2011

For patients with colon cancer, what is the comparative effectiveness of multi-parameter gene expression assays (e.g., Oncotype DX® colon cancer test*) versus standard clinical and pathological risk f ...

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June 1, 2011

For patients with breast, colorectal, and lung cancers, what is the comparative effectiveness for improving net health outcome of more versus less frequent follow-up imaging to monitor for recurrence ...

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June 1, 2011

For patients with ovarian cancer, what is the comparative effectiveness of surveillance using serum cancer antigen 125 (CA 125) versus standard methods (based on clinical symptoms or signs of disease) ...

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June 1, 2011

For patients with advanced or metastatic solid tumors such as non-small cell lung cancer, what is the comparative effectiveness of usual care plus interdisciplinary palliative care versus usual care a ...

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