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Department of Health and Human Services

Read Suggested Topics for Research

Browse or use the search box below to see suggestions submitted by others. Click on the text link to read the full suggestion. Suggestions are presented as they were submitted and are not edited. See Search for Guides, Reviews, and Reports for research in progress and final reports.

Suggestions that have completed the Program's selection process are identified by a topic suggestion disposition (PDF). Suggestions submitted prior to 2008 were reviewed under a different process and disposition reports may not be available.


Dec. 19, 2011

For patients undergoing major surgical procedures, what is the comparative effectiveness of post-operative ICU care vs non-ICU care?

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Dec. 19, 2011

Preliminary Key Questions 1. What are the outcomes (effectiveness and harms) of carotid artery stenting (CAS) compared to carotid endarterectomy (CEA)? 2. Are there patient subgroups who are likely ...

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Dec. 13, 2011

Would a combination MBSR and CT intervention be successful for adults with Type II diabetes who have persistently high A1C levels despite being on insulin?

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Dec. 6, 2011

We are interested in the comparative effectiveness of Vitamin D supplementation in the prevention of chronic kidney disease (CKD). All forms of Vitamin D supplementation could be examined, and compar ...

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Dec. 6, 2011

We are interested in the comparative effectiveness of diabetes control/management strategies in the prevention of CKD. To evaluate this area, optimal glycemic targets first need to be established in t ...

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Dec. 6, 2011

We are interested in the comparative effectiveness of patient safety interventions in decreasing the incidence of acute kidney injury (AKI). This includes questions related to interventions focused on ...

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Nov. 8, 2011

for patients receiving pulmonary therapy for COPD, would results be improved by normalizing blood gases and relieving dynamic lung hyperinflation prior to therapy.

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Nov. 1, 2011

Fibromyalgia. Very few doctors know how to treat this pain. Some states, there are really none. More & more are being diagnosed, but no treatment especially with severe pain. Fibro brings on IBS, mi ...

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Oct. 19, 2011

What is best practice for third stage management during childbirth?

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Oct. 11, 2011


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Oct. 4, 2011

i take diltiazem for my a fib. i am allegic to warfarin. i have found nattokinase (cardiokinase) from to really work fantastic for me- no danger of clots. my doctor and i am a ...

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Sept. 24, 2011

Reproductive health among urban slump

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Sept. 9, 2011

Comparative effectiveness of ultrasound, conventional computed tomography (CT), multidetector computed tomography (MDCT), magnetic resonance imaging (MRI) (using conventional VS novel contrast agents) ...

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Sept. 9, 2011

What is the comparative effectiveness of imaging techniques (e.g. CT scans versus chest X-rays) for monitoring of solitary lung nodules?

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Sept. 9, 2011

What is the effectiveness of the use of pharmacological interventions (FDA approved) in treating alcohol-use disorders in primary care settings?

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Sept. 8, 2011

In view of the latest Affordable Care & Health Reform legislation, how will keeping weak national and individual state-by-state lack of full recognition for autonomous practice in primary care for “no ...

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Sept. 7, 2011

Women are disproportionately affected with thyroid disorders. When I was diagnosed with moderate hyperthyroidism of the Graves' type, I was told that only surgery to remove my entire gland or radioabl ...

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Aug. 23, 2011

For patients with Narcolepsy and sleep paralysis, is there an effective treatment that wont have bad side effects?

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Aug. 15, 2011

treatment that this program shold consider&health care test

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Aug. 15, 2011

For patients with common variable immune deficiency receiving intravenous immunoglobulin therapy (IVIG), what is the difference in long term outcomes for those who receive treatment in their homes vs. ...

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Aug. 4, 2011

In order to prevent the 350,000 annual sudden cardiac deaths a year in the USA and the 21% of unnecessary implanted defibrillator patients why is Cambridge Hearts Microvolt T-Wave Alternans Test a gui ...

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July 27, 2011

In patients with cerebral palsy (CP) and difficulties with feeding, what is the effectiveness of of anti-reflux procedure (since often done in conjunction with gastrostomy placement) or type of tube ...

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July 26, 2011

For Rehab patients, what is the comparative effectiveness of a coordinated primary health care team following the patient with the usual care of hospitalization to home health>

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July 22, 2011

•How effective is Balneotherapy—the therapeutic use of mineral and thermal waters -- for improving the mobility of patients suffering from chronic diseases such as rheumatoid arthritis, fibromyalgia, ...

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July 13, 2011

Percentage of microscopic validation of acute inflammation among appendices removed for acute abdominal pain?

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