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First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness

Slide: 11 of 35

Clinically Significant Outcomes of Interest in the Comparative Effectiveness Review (1 of 3)

A variety of validated assessment instruments are used to measure outcomes of treating schizophrenia and bipolar disorder with antipsychotics.

Scales are used both in practice and in clinical studies. Remission rates and changes in symptom severity are reported. Response rate is defined as the proportion of participants achieving a degree of improvement (specified a priori) on a rating scale. The primary instruments used in the included studies and analyzed in the comparative effectiveness review are presented in tables in the following slides.