Noninvasive Positive-Pressure Ventilation for Acute Respiratory Failure: Comparative Effectiveness
Clinical Questions Addressed by This Comparative Effectiveness Review (1 of 3)
This comparative effectiveness review attempted to address four key questions. Key Question 1 is listed on this slide:
Is noninvasive positive-pressure ventilation associated with less morbidity (including from intubation), lower mortality, lower adverse events, or lower medical utilization when compared with supportive medical therapy or invasive ventilation:
a. In adults with chronic obstructive pulmonary disease and acute respiratory failure?
b. In adults with acute cardiogenic pulmonary edema?
c. In adults with acute respiratory failure due to other causes including pneumonia, asthma, obesity hypoventilation syndrome, and interstitial lung disease?
d. In adults with acute respiratory failure in selective settings, including the postoperative setting and the post-transplant setting?
- Williams JW Jr, Cox CE, Hargett CW, et al. Noninvasive Positive-Pressure Ventilation (NPPV) for Acute Respiratory Failure: Comparative Effectiveness. Comparative Effectiveness Review No. 68 (Prepared by the Duke Evidence-based Practice Center under Contract No. 290-2007-10066-I). Rockville, MD: Agency for Healthcare Research and Quality; July 2012. AHRQ Publication No. 12-EHC089-EF. Available at www.effectivehealthcare.ahrq.gov/nppv.cfm.
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