Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Testing for the Evaluation of Musculoskeletal Complaints in Pediatric Populations
Report Findings: Etiology of Musculoskeletal Pain Among Healthy Children
According to one retrospective chart review, 97 percent of musculoskeletal pain in children was of noninflammatory origin. The most common cause is physical trauma (44%). Other causes include overuse (24%), osteochondroses (10.3%), hypermobility (3.3%), growing pain (3.5%), and viral infection (4.5%). The prevalence of these etiologies varies with age.
Keywords: musculoskeletal pain | healthy children | etiology | physical trauma | overuse | osteochondroses | hypermobility | growing pain | viral infection | prevalence
- Wong KO, Bond K, Homik J, et al. Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children. Comparative Effectiveness Review No. 50 (Prepared by the University of Alberta Evidence-based Practice Center under Contract No. HHSA 290-2007-10021-I). Rockville, MD: Agency for Healthcare Research and Quality; March 2012. AHRQ Publication No. 12-EHC015-EF. Available at www.effectivehealthcare.ahrq.gov/anatest.cfm.
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