Treatment Options for Attention Deficit Hyperactivity Disorder
Adverse Effects (2 of 3)
Overall, more adverse effects were reported in preschoolers than in primary school children. Moodiness and irritability often led to discontinuation of treatment with MPH. ADHD medications appear to have a small but distinct dose-related impact on growth rates in children. Some studies found that although children taking ADHD medications appear to have diminished growth rates, they may eventually catch up on their growth over time. Safety investigations from observational studies and administrative databases did not provide conclusive evidence for cardiovascular or cerebrovascular adverse effects.
- Charach A, Dashti B, Carson P, et al. Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers; Long-Term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment. Comparative Effectiveness Review No. 44 (Prepared by McMaster University Evidence-based Practice Center under Contract No. MME 2202 290-02-0020). Rockville, MD: Agency for Healthcare Research and Quality; October 2011. AHRQ Publication No. 11(12)-EHC003-EF. Available at www.effectivehealthcare.ahrq.gov/adhdtreatment.cfm.
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