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Adjunctive Devices for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention

Slide: 21 of 39

Adjunctive Catheter Aspiration Thrombectomy Versus PCI Alone in Patients With STEMI: Final Health Outcomes

In the meta-analyses of the RCTs comparing adjunctive catheter aspiration devices to PCI alone, the use of catheter aspiration devices significantly decreased the risk of MACE with a high strength of evidence rating. Given the risk difference [RD -0.03 (-0.01, 0.001), CER (0.02 to 0.35)], 33 people would need to be treated with a catheter aspiration device to prevent one MACE. However, it did not significantly impact mortality, MI, or target revascularization versus a control using the maximal duration of followup with a low strength of evidence rating.

One direct comparative randomized trial compared the use of one catheter aspiration device to another in patients with STEMI. In this controlled trial, no significant differences in MI, target revascularization, or MACE were found at the longest duration of followup with the other final health outcomes not being evaluated.