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Analgesics for Osteoarthritis—An Update

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Clinical Questions Addressed by the CER (2 of 2)

In preparing the report on which this CME activity is based, the authors aimed to answer four KQs. KQs 3 and 4 are listed below:

KQ 3: What are the comparative benefits and adverse effects of coprescribing H2-antagonists, misoprostol, or proton pump inhibitors (PPIs) on the GI adverse effects associated with NSAID use?

KQ 4: What are the comparative benefits and adverse effects of treating osteoarthritis with oral medications as compared with topical preparations, or of different topical medications compared with one another?