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Management of an Adult With Type 2 Diabetes With Antidiabetic Medications: A Case Scenario

Slide: 9 of 26

Risk Reduction Associated With Glycemic Control

You explain that current research shows there is good evidence that achieving excellent glycemic control (an HbA1c of 7%) may offer him:

Discussion of Answers:

A. Incorrect. Explanation: There is currently no strong evidence that excellent glycemic control alone (i.e., in the absence of treatment of other risk factors) is associated with reduced risk of mortality, myocardial infarction, or diabetes-related hospitalizations.

B. Incorrect. Explanation: There is currently no strong evidence that excellent glycemic control alone (i.e., in the absence of treatment of other risk factors) is associated with reduced risk of mortality, myocardial infarction, or diabetes-related hospitalizations.

C. Incorrect. Explanation: There is currently no strong evidence that excellent glycemic control alone (i.e., in the absence of treatment of other risk factors) is associated with reduced risk of mortality, myocardial infarction, or diabetes-related hospitalizations.

D. Correct. Explanation: Results from randomized controlled trials have demonstrated that the risk of microvascular complications, particularly retinopathy, can be reduced by improved glycemic control in patients with type 2 diabetes. Studies have had only mixed results regarding the impact of intensive glycemic control (HbA1c <7%) on cardiovascular events and/or mortality.

E. Explanation: There is currently no strong evidence that excellent glycemic control alone (i.e., in the absence of treatment of other risk factors) is associated with reduced risk of mortality, myocardial infarction, or diabetes-related hospitalizations.