Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer
External-Beam Radiation Therapy for Head and Neck Cancer
The main challenge in using radiation therapy to treat cancer is to attain the highest probability of tumor control or cure with the least amount of morbidity and toxicity to normal surrounding tissues (sometimes referred to as organs at risk). The external-beam radiation therapy modalities used to treat head and neck cancer include two-dimensional radiation therapy, three-dimensional conformal radiation therapy, intensity-modulated radiation therapy, and proton beam therapy. Each of these modalities has been developed as an attempt to improve the conformality of the radiation being delivered. In other words, getting radiation just to the tumor and not to the normal surrounding tissue that could be harmed during treatment.
Keywords: 2DRT | 3DCRT | head and neck cancer | IMRT | proton beam therapy | treatment | radiotherapy
- Samson DJ, Ratko TA, Rothenberg BM, et al. Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer, Comparative Effectiveness Review No. 20 (Prepared by the Blue Cross and Blue Shield Association Technology Evaluation Center Evidence-based Practice Center under Contract No. 290-02-0026). Rockville, MD: Agency for Healthcare Research and Quality; May, 2010. AHRQ Publication No. 10-EHC014-EF.
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