Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer
Risk Factors for Head and Neck Cancer
Major risk factors for the development of head and neck cancer include tobacco and alcohol abuse, with other less-common risk factors including occupational exposures, nutritional deficiencies, and poor oral health. Viral etiologies have also been established, with human papillomavirus infection appearing to be a risk factor, particularly within the oropharynx, in younger people without a history of tobacco or alcohol abuse. In addition, an association has been made between Epstein-Barr virus and nasopharyngeal cancer.
- Samson DJ, Ratko TA, Rothenberg BM, et al. Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer, Comparative Effectiveness Review No. 20 (Prepared by the Blue Cross and Blue Shield Association Technology Evaluation Center Evidence-based Practice Center under Contract No. 290-02-0026). Rockville, MD: Agency for Healthcare Research and Quality; May, 2010. AHRQ Publication No. 10-EHC014-EF.
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