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First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness

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Comparative Effectiveness of FGAs and SGAs for Treating Schizophrenia: Response and Remission Rates

Few statistically significant differences in other outcomes (e.g., response and remission rates, utilization of the health care system) were found.

When compared with haloperidol, risperidone yields better relapse rates and olanzapine provides better response and relapse rates in patients with schizophrenia. The strength of evidence for this finding was not rated.