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First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness

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First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness

This slide set is based on a comparative effectiveness review (CER) First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness, which was developed by the University of Alberta Evidence-based Practice Center for the Agency for Healthcare Research and Quality under Contract No. 290-2007-10021 and is available online at www.effectivehealthcare.ahrq.gov/antipsychotics-adult.cfm.

CERs are comprehensive systematic reviews of the literature that usually compare two or more types of treatment, such as different drugs or adding a second drug to usual care for the same disease. The literature included in this review was identified in searches for trials and studies that explicitly compared first-generation with second-generation antipsychotics for the approved indications of schizophrenia and bipolar disorder in adults ages 18–64. Searches were conducted for studies published through July 2011.