Drug Therapy for Rheumatoid Arthritis in Adults
Treatment of Rheumatoid Arthritis
The goal of RA treatment is to control pain, control inflammation, limit progressive damage, and reduce disease activity or induce remission.
Disease-modifying anti-rheumatic drugs (DMARDs) interfere with rheumatoid disease processes by blocking the production or activity of the immune cells and their products that cause inflammation and damage. Treatment with DMARDs is increasing with the expectation that they will lead to better disease control and more remissions. Corticosteroids—both low-dose systemic and intra-articular formulations—are used as adjuncts to DMARD treatment.
Keywords: rheumatoid arthritis | RA | DMARDs | disease-modifying | antirheumatic | anti-rheumatic | rheumatic | biologic | oral | corticosteroids
- Donahue KE, Jonas D, Hansen RA, et al. Drug Therapy for Rheumatoid Arthritis in Adults: An Update. Comparative Effectiveness Review No. 55 (Prepared by the RTI International–University of North Carolina Evidence-based Practice Center under Contract No. 290-2007-10056-I). Rockville, MD: Agency for Healthcare Research and Quality; April 2012. AHRQ Publication No. 12-EHC025-EF. Available at www.effectivehealthcare.ahrq.gov/dmardsra.cfm.
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