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Drug Therapy for Rheumatoid Arthritis in Adults

Slide: 31 of 45

Summary of Results: DMARD Combinations Versus Monotherapies

In patients with early rheumatoid arthritis who had not been treated with methotrexate (MTX), or who had not received MTX in the previous 3 months, head–to–head comparisons of combination therapy and MTX monotherapy were examined for effects on function and quality of life. Combination therapy was more effective in achieving improvements in function and quality of life. The strength of evidence is moderate for functional status and low for quality of life.