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Noninvasive Positive-Pressure Ventilation for Acute Respiratory Failure: Comparative Effectiveness

Slide: 22 of 25

Conclusions (1 of 2)

For patients with acute respiratory failure due to severe exacerbations of chronic obstructive pulmonary disease or acute cardiogenic pulmonary edema (ACPE), the use of noninvasive positive-pressure ventilation (NPPV) plus supportive medical therapy was associated with reductions in mortality, intubation rates, and hospital-acquired pneumonia when compared with supportive medical therapy alone.

In a limited number of patients, the use of NPPV decreased hospital-acquired pneumonia when compared with invasive ventilation.