Disease-Modifying Antirheumatic Drugs in Children With Juvenile Idiopathic Arthritis
Evaluating JIA Assessment Instruments: Conclusions (1 of 2)
No one instrument or outcomes measure appears to be superior in measuring disease activity or functional status. Reliability and validity are moderate for the physical scales of most measures examined but are poor in the psychosocial domains.
The Child Health Assessment Questionnaire (CHAQ) is the most commonly reported instrument to assess health/disease status for patients with JIA; it shows moderate to high validity and reliability. CHAQ responsiveness appears to be affected by disease subtype and baseline severity.
Keywords: juvenile idiopathic arthritis | JIA | JRA | juvenile rheumatoid arthritis | JCA | DMARDs | disease-modifying | antirheumatic | anti-rheumatic | rheumatic | TNF-alpha blockers | biologic DMARD | nonbiologic DMARD | non-biologic DMARD | assessment | validity | reliability | responsiveness | CHAQ
- Kemper A, Coeytaux R, Sanders G, et al. Disease-Modifying Antirheumatic Drugs (DMARDs) in Children With Juvenile Idiopathic Arthritis (JIA). Comparative Effectiveness Review No. 28 (Prepared by the Duke Evidence-based Practice Center under Contract No. HHSA 290-2007-10066-I). Rockville, MD: Agency for Healthcare Research and Quality; September 2011. AHRQ Publication No. 11-EHC039-EF. Available at www.effectivehealthcare.ahrq.gov/dmardsjia.cfm.
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