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Disease-Modifying Antirheumatic Drugs in Children With Juvenile Idiopathic Arthritis

Slide: 32 of 46

Studies Reporting Adverse Effects Associated With DMARDs

Thirteen randomized controlled trials describing 14 DMARD interventions included a placebo comparison and reported adverse effects; 914 unique patients were included.

One hundred fifty-one publications reported adverse effects in patients with JIA and treated with DMARDs; 4,344 patients were included. Patient populations in the reports may overlap with randomized controlled trials and with each other.

Two studies reported cases of malignancies in children undergoing DMARD treatment for JIA. The patient populations of these studies were not identified.