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Disease-Modifying Antirheumatic Drugs in Children With Juvenile Idiopathic Arthritis

Slide: 21 of 46

Summary of Results: Adding Nonbiologic DMARDs to JIA Treatment

Adding methotrexate to anti-inflammatory treatments improves disease activity, as scored by physicians. The strength of evidence in support of this finding is moderate.

The results for other nonbiologic DMARDs are inconsistent and often statistically nonsignificant. For many outcomes, no observations are available. The evidence is insufficient to permit conclusions about benefits of nonbiologic DMARDs other than methotrexate.