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Off-Label Use of Atypical Antipsychotics: An Update

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Adverse Effects of Atypical Antipsychotics

The reviewed data were restricted to reports in studies of off-label use of atypical antipsychotics. With the exception of dementia, which is associated with older age, the adverse effects observed were not expected to be influenced by the diagnosis. Evidence was analyzed for two separate groups: elderly patients with dementia and adults aged 18–64.

The atypical antipsychotic clozapine was not included in the review; clozapine can only be prescribed in a system that requires weekly monitoring for bone marrow-suppression disorders before providing the drug.