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Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Testing for the Evaluation of Musculoskeletal Complaints in Pediatric Populations

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Report Findings: Etiology of Musculoskeletal Pain Among Healthy Children

According to one retrospective chart review, 97 percent of musculoskeletal pain in children was of noninflammatory origin. The most common cause is physical trauma (44%). Other causes include overuse (24%), osteochondroses (10.3%), hypermobility (3.3%), growing pain (3.5%), and viral infection (4.5%). The prevalence of these etiologies varies with age.