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Comparative Effectiveness of Management Strategies for Adults With Gastroesophageal Reflux Disease: An Update

Slide: 9 of 26

Clinical Questions Addressed by the CER (1 of 3)

In preparing the report on which this continuing medical education (CME) activity is based, the authors aimed to answer three Key Questions. Key Question 1 is listed below:

  • What is the evidence of the comparative effectiveness of medical, surgical, and other newer forms of treatments for improving objective and subjective outcomes in patients with chronic GERD?
  • Is there evidence that effectiveness varies by specific technique, procedure, or medication?
  • Objective outcomes addressed include esophagitis healing, ambulatory pH monitoring, other indicators of reflux, medication need, health care utilization, and incidence of esophageal stricture, Barrett's esophagus or esophageal adenocarcinoma.Subjective outcomes include symptom frequency and severity, sleep/productivity, and overall quality of life.

CER = comparative effectiveness review
GERD = gastroesophageal reflux disease