Comparative Effectiveness of Management Strategies for Adults With Gastroesophageal Reflux Disease: An Update
Findings of the Comparative Effectiveness Review: Medication (3 of 3)
Evidence was insufficient concerning the effectiveness of GERD treatment for relieving asthma symptoms. Evidence of low strength indicates that the following adverse effects were associated with PPI treatment: diarrhea, nausea or vomiting, abdominal pain, dyspepsia, headache, intestinal infection, pneumonia, and increased risk of bone fracture.
GERD = gastroesophageal reflux disease
PPI = proton pump inhibitor
Keywords: GERD | histamine type 2 receptor antagonist | H2RA | proton pump inhibitor | PPI | extraesophageal
- Ip S, Chung M, Moorthy D, et al. Comparative Effectiveness of Management Strategies for Adults With Gastroesophageal Reflux Disease: An Update. Comparative Effectiveness Review No. 29 (Prepared by the Tufts Evidence-based Practice Center under Contract No. HHSA 290-2007-10055-I). Rockville, MD: Agency for Healthcare Research and Quality; September 2011. AHRQ Publication No. 11-EHC049-EF. Available at www.effectivehealthcare.ahrq.gov/gerdupdate.cfm.
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