Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: An Update
Fracture risk reduction is greatest in women with established osteoporosis and/or prevalent fractures, and reduction of fracture risk from treatment is not dependent on patient age. Older individuals are as likely to benefit from treatment as younger individuals. The strength of evidence in support of this conclusion is high.
Women with established osteoporosis benefit more from treatment than women with osteopenia and without prevalent fractures.
Most authorities no longer consider calcitonin to be an appropriate treatment for osteoporosis, yet it is still widely prescribed. Evidence supports the conclusion that it is not effective in postmenopausal women with osteoporosis.
Keywords: bone | low bone density | bone density | osteoporosis | fracture | osteopenia | skeletal | risk | age | calcitonin | postmenopausal
- Newberry SJ, Crandall CC, Gellad WG, et al. Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: An Update to the 2007 Report. Comparative Effectiveness Review No. 53 (Prepared by the Southern California Evidence-based Practice Center under Contract No. HHSA 290-2007-10062-I). Rockville, MD: Agency for Healthcare Research and Quality; February 2012. AHRQ Publication No. 12-EHC023-EF. Available at www.effectivehealthcare.ahrq.gov/reports/lbd.cfm.
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