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Non-surgical Treatments for Urinary Incontinence in Adult Women: Diagnosis and Comparative Effectiveness

Slide: 49 of 50

Gaps in Knowledge

The systematic review revealed areas where the evidence about treatments for UI is limited or absent, including:

Evidence is insufficient to permit conclusions about he effectiveness of nonpharmacological interventions compared with drugs and comparisons of continence services, group or individual therapy, behavioral weight loss and education, or combined modalities.

Evidence about long-term safety of drug treatments for UI is insufficient to permit conclusions.

The reasons for high discontinuation rates with nonpharmacological interventions and methods to improve adherence are not understood nor well investigated.

Evidence is inadequate to determine whether increasing drug dosage leads to greater improvement or likelihood of achieving continence.

Evidence about how patient characteristics influence the treatment benefits or adverse effects of treatment is incomplete and of limited value to guide decisionmaking (e.g., baseline frequency, age, race, type of UI, prior treatment, comorbidities, and obesity).