Non-surgical Treatments for Urinary Incontinence in Adult Women: Diagnosis and Comparative Effectiveness
Additional Information About Adverse Effects
Evidence about long-term safety of drug treatments for UI is insufficient to permit conclusions about the magnitude of risk. Postmarketing surveillance has revealed increased risks of ventricular arrhythmias or sudden death when used in older people who are also using antihistamines or cytochrome inhibitors. Tolterodine is associated with an increased risk of hallucinations.
Keywords: urinary incontinence | stress incontinence | urge incontinence | urgency incontinence | mixed incontinence | continence | adverse effects | darifenacin | fesoterodine | oxybutynin | solifenacin | discontinuation | dosage | trospium | tolterodine
- Shamliyan T, Wyman J, Sainfort F, et al. Nonsurgical Treatments for Urinary Incontinence in Adult Women: Diagnosis and Comparative Effectiveness. Comparative Effectiveness Review No. 36 (Prepared by the Minnesota Evidence-based Practice Center under Contract No. 290-2007-10064-I). Rockville, MD: Agency for Healthcare Research and Quality; April 2012. AHRQ Publication No. 11(12)-EHC074-EF. Available at www.effectivehealthcare.ahrq.gov/ui.cfm.
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