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Noncyclic Chronic Pelvic Pain Therapies for Women

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Background: Burden of Noncyclic CPP

CPP carries a significant quality-of-life burden in terms of sexual functioning, depression, fatigue, and physical limitations and disability associated with pain. Women with CPP tend to report lower general physical health scores than women without pain. Women with CPP describe loss, social isolation, and effects on relationships and have a high incidence of comorbidity, sleep disturbance, and fatigue.

CPP, both cyclic and noncyclic, accounts for about 1 in 10 outpatient gynecology visits and is the indication for an estimated 15 to 40 percent of laparoscopies and 12 percent of hysterectomies in the United States. An estimated $1.2 billion per year are spent on outpatient management of CPP in the United States. In addition, the total indirect cost due to time lost from work is estimated to be $760 million per year.