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Noncyclic Chronic Pelvic Pain Therapies for Women

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Background: Etiology of Noncyclic CPP

The pathophysiology of chronic pelvic pain is complex and is not well understood. Noncyclic CPP frequently has more than one underlying cause. Potential causes for noncyclic CPP that have been identified include:

  • Gynecological causes such as endometriosis, pelvic inflammatory disease, adhesions and pelvic floor muscle spasm 
  • Gastrointestinal causes such as irritable bowel syndrome or IBS, celiac disease and inflammatory bowel disease
  • Urologic causes such as interstitial cystitis or painful bladder syndrome and chronic urinary tract infection
  • Musculoskeletal causes such as myofascial pain disorders, fibromyalgia and degenerative disk disease
  • Psychiatric/neurologic causes such as depression, neurologic dysfunction, abdominal epilepsy and sleep disturbance

The four most commonly diagnosed etiologies for noncyclic CPP are endometriosis, adhesions, IBS, and IC.

The multifactorial etiology of noncyclic CPP complicates diagnosis, and a definitive diagnosis is not made for 61 percent of women with CPP.