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Noncyclic Chronic Pelvic Pain Therapies for Women

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Conclusions (1 of 2)

A thorough work-up that includes gynecological, gastrointestinal, urological and/or psychological assessments may be required in patients with CPP given the complex etiology of this condition.

The currently available evidence is based largely on poor-quality studies with significant heterogeneity in study populations and design. Limited evidence suggests that patients with CPP where endometriosis is suspected may benefit from hormonal therapy. However, this evidence cannot be extrapolated to patients without clinically suspected endometriosis. Among surgical approaches for CPP, both LUNA and laparoscopic adhesiolysis were not found to be superior to diagnostic laparoscopy in improving pain or quality of life.

Available evidence is insufficient to change current clinical strategies for managing CPP. For this reason, use of less-invasive diagnostic and therapeutic interventions may be warranted before moving on to strategies that are more invasive and may be associated with increased risk of harms.