Noncyclic Chronic Pelvic Pain Therapies for Women
Prevalence of Comorbidities in Women With Noncyclic CPP
Twenty-six studies were reviewed that assessed the prevalence of comorbidities. Of the 26 included studies, 16 were observational studies and 7 were randomized controlled trials (RCTs). Most of the studies were of fair or poor quality. None of the identified studies addressed temporomandibular joint pain disorder, fibromyalgia, complex regional pain syndrome, functional abdominal pain syndrome, or anxiety disorder. The most common comorbidities were dyspareunia, dysmenorrhea, and IBS.
Dyspareunia: Eleven studies reported on prevalence of dyspareunia with rates of 15 to 88 percent (median 54%).
Dysmenorrhea: Twelve studies reported the prevalence of dysmenorrhea with rates of 4 to 100 percent (median 86%).
IBS: Ten studies reported prevalence rates for IBS. Of these, six studies used Rome I or Rome II criteria for IBS diagnosis. These studies reported prevalence rates of 24 to 39 percent (median 35%).
The prevalence rates for the comorbidities we examined showed significant variation due to inconsistencies in operational definitions or diagnostic criteria for comorbidities. Prevalence estimates tended to be narrower for some conditions (e.g., IBS) where standardized diagnostic criteria were used. Additionally, some conditions could be etiological factors for CPP or co-occur with CPP, adding to the complexity in diagnosing the condition.
Strength of evidence: The strength of evidence was not assessed for this KQ since it did not discuss effectiveness of interventions.
- Andrews J, Yunker A, Reynolds WS, et al. Noncyclic Chronic Pelvic Pain Therapies for Women: Comparative Effectiveness. Comparative Effectiveness Review No. 41 (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I). Rockville, MD: Agency for Healthcare Research and Quality; January 2012. AHRQ Publication No. 11(12)-EHC088-EF. Available at www.effectivehealthcare.ahrq.gov/pelvicpain.cfm.
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