Analgesics for Osteoarthritis—An Update
Conclusions (1 of 2)
When analgesics are compared to each other, none appears to offer greater benefits relative to adverse effects a this time. Trade-offs between benefits and adverse effects appear to differ across analgesics, increasing the need to consider individual patient priorities when choosing among these medications. No significant differences were found in the benefits offered by NSAIDs; however, differences in GI adverse effects must be balanced with associated CV risks.
Keywords: conclusions | analgesics | NSAIDs | benefits | adverse effects | GI risks | CV risks | trade-offs | patient priorities
- Chou R, McDonagh M, Nakamoto E, et al. Comparative Effectiveness and Safety of Analgesics for Osteoarthritis: An Update of the 2006 Report. Comparative Effectiveness Review No. 38 (Prepared by Oregon Evidence-based Practice Center under Contract No. HHSA 290-2007-10057-I). Rockville, MD: Agency for Healthcare Research and Quality; October 2011. AHRQ Publication No. 11(12)-EHC076-EF. Available at: http://www.effectivehealthcare.ahrq.gov/reports/analgesicsupdate.cfm.
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