Analgesics for Osteoarthritis—An Update
Clinical Questions Addressed by the CER (2 of 2)
In preparing the report on which this CME activity is based, the authors aimed to answer four KQs. KQs 3 and 4 are listed below:
KQ 3: What are the comparative benefits and adverse effects of coprescribing H2-antagonists, misoprostol, or proton pump inhibitors (PPIs) on the GI adverse effects associated with NSAID use?
KQ 4: What are the comparative benefits and adverse effects of treating osteoarthritis with oral medications as compared with topical preparations, or of different topical medications compared with one another?
- Chou R, McDonagh M, Nakamoto E, et al. Comparative Effectiveness and Safety of Analgesics for Osteoarthritis: An Update of the 2006 Report. Comparative Effectiveness Review No. 38 (Prepared by Oregon Evidence-based Practice Center under Contract No. HHSA 290-2007-10057-I). Rockville, MD: Agency for Healthcare Research and Quality; October 2011. AHRQ Publication No. 11(12)-EHC076-EF. Available at: http://www.effectivehealthcare.ahrq.gov/reports/analgesicsupdate.cfm.
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