Diagnosis and Treatment of Obstructive Sleep Apnea in Adults
Comparative Effectiveness of Continuous Positive Airway Pressure Machines
Autotitrated continuous positive airway pressure (autoCPAP) is a CPAP device that automatically adjusts the level of delivered pressure based on the patient’s requirements. There is moderate strength of evidence that autoCPAP and fixed continuous positive airway pressure (CPAP) result in similar compliance and treatment effects for patients with obstructive sleep apnea (OSA). There is low strength of evidence that there is no substantial difference in compliance or other outcomes between flexible CPAP (adjusts air pressure to accommodate exhalation) and CPAP. The strength of evidence is insufficient regarding comparisons of different CPAP devices or modifications, such as oral CPAP, nasal CPAP, bilateral positive airway pressure (PAP), flexible bilateral PAP, and humidified CPAP or autoCPAP. It is important to note that current research evaluates only intermediate outcomes, and thus these findings may not apply to long-term clinical outcomes.
Keywords: outcomes | treatment | strength of evidence | continuous positive airway pressure | CPAP | positive airway pressure | PAP
- Balk EM, Moorthy D, Obadan NO, et al. Diagnosis and Treatment of Obstructive Sleep Apnea in Adults. Comparative Effectiveness Review No. 32 (Prepared by Tufts Evidence-based Practice Center under Contract No. 290-2007-10055-I). Rockville, MD: Agency for Healthcare Research and Quality; July 2011. AHRQ Publication No. 11-EHC052-EF.
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