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Diagnosis and Treatment of Obstructive Sleep Apnea in Adults

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Correlation of AHI with Health Outcomes

There is a high strength of evidence that an apnea-hypopnea index (AHI) ≥ 30 events per hour (HR, 1.5-3.0) is an independent predictor of all-cause mortality, although one study found that this was true only in men under the age of 70 years. There is a low strength of evidence that a higher AHI (AHI ≥ 8 events per hour, in one study; Botros, 2009) is associated with incident diabetes (OR, 2.81-4.06), though possibly confounded by obesity, which may result in both OSA and diabetes. The strength of evidence is insufficient to determine the association between AHI and other clinical outcomes.