Comparing Medications for Adults With Type 2 Diabetes
Macrovascular and Microvascular Long-Term Clinical Outcomes of Diabetes
There were 41 new studies identified in addition to the 25 studies included in the 2007 evidence report that addressed long-term clinical outcomes such as mortality, cardiovascular disease, stroke, retinopathy, nephropathy, and neuropathy. However, the new studies were generally of short duration (less than 1 year) and had few long-term events (such as death and cardiovascular disease), making any estimates of risk difference very imprecise. Therefore, most comparisons for this key question had a low strength of evidence.
Keywords: macrovascular | microvascular | long-term outcomes | mortality | cardiovascular mortality | morbidity
- Bennett WL, Wilson LM, Bolen S, et al. Oral Diabetes Medications for Adults With Type 2 Diabetes: An Update. Comparative Effectiveness Review No. 27. (Prepared by Johns Hopkins University Evidence-based Practice Center under Contract No. 290-02-0018.) AHRQ Publication No. 11-EHC038-EF. Rockville, MD: Agency for Healthcare Research and Quality. March 2011. Available at: http://effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-reports/?pageaction=displayproduct&productID=644.
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