Traumatic Brain Injury and Depression
Background: Treatment Options for Depression Examined in the Systematic Review
Potential treatment options for depression examined in this systematic review are drawn from the current armamentarium of treatments for non–TBI-related depression and include: psychotherapy, psychotropic medications, neuropsychological rehabilitation, community-based rehabilitation, complementary and alternative medicine, and neuromodulation therapies. Psychotropic medications may include: selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, tricyclic antidepressants, monoamine oxidase inhibitors, and other, non–FDA-approved uses of both older and novel medications.
- Guillamondegui OD, Montgomery SA, Phibbs FT, et al. Traumatic Brain Injury and Depression. Comparative Effectiveness Review No. 25 (Prepared by Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I). Rockville, MD: Agency for Healthcare Research and Quality; March 2011. AHRQ Publication No. 11-EHC017-EF. Available at: www.effectivehealthcare.ahrq.gov/reports/final.cfm.
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