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Traumatic Brain Injury and Depression

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Traumatic Brain Injury and Depression Evidence Report: Key Questions 1–3

In preparing the report on which this continuing medical education (CME) activity is based, the authors aimed to answer six Key Questions. Key Questions 1–3 are listed below:

KQ1. What is the prevalence of depression after TBI, and does the area of the brain injured, the severity of the injury, the mechanism or context of injury, or time to recognition of the TBI or other patient factors influence the probability of developing clinical depression?

KQ2. When should patients who suffer TBI be screened for depression, with what tools, and in what setting?

KQ3. Among individuals with TBI and depression, what is the prevalence of concomitant psychiatric/behavioral conditions, including anxiety disorders, post-traumatic stress disorder (PTSD), substance abuse, and major psychiatric disorders?