Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer
Conclusions on the Comparative Effectiveness Regarding Quality of Life and Adverse Events: IMRT vs. 2DRT
Patients who receive IMRT have reduced late xerostomia and better quality of life (as it relates to late xerostomia) when compared with those who receive 2DRT [Level of Evidence: Moderate]. There is insufficient evidence to permit conclusions about other outcomes related to adverse events and quality of life.
Keywords: 2DRT | adverse events | head and neck cancer | IMRT | outcomes xerostomia | quality of life | radiotherapy | comparative effectiveness
- Samson DJ, Ratko TA, Rothenberg BM, et al. Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer, Comparative Effectiveness Review No. 20 (Prepared by the Blue Cross and Blue Shield Association Technology Evaluation Center Evidence-based Practice Center under Contract No. 290-02-0026). Rockville, MD: Agency for Healthcare Research and Quality; May 2010. AHRQ Publication No. 10-EHC014-EF.
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