Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer
Clinical Bottom Line: Comparative Evidence for 2DRT, 3DCRT, and IMRT
This slide summarizes the most pertinent results regarding tumor control, survival, and adverse events from the comparative effectiveness review (CER) titled, Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer. The next several slides (25–34) will discuss these data in greater detail. When considered together, the results indicate that there may be a clinical benefit from IMRT for some patients with head and neck cancer in terms of the occurrence of late xerostomia and quality of life related to xerostomia.
Keywords: 2DRT | 3DCRT | adverse events | head and neck cancer | IMRT | outcomes | quality of life | radiotherapy | survival | tumor control | xerostomia | comparative effectiveness
- Samson DJ, Ratko TA, Rothenberg BM, et al. Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer, Comparative Effectiveness Review No. 20 (Prepared by the Blue Cross and Blue Shield Association Technology Evaluation Center Evidence-based Practice Center under Contract No. 290-02-0026). Rockville, MD: Agency for Healthcare Research and Quality; May 2010. AHRQ Publication No. 10-EHC014-EF.
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