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  • Assessment of the Need to Update Comparative Effectiveness Reviews: Report of an Initial Rapid Program Assessment (2005-2009)

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Abstract - Final – Sept. 22, 2009

Assessment of the Need to Update Comparative Effectiveness Reviews: Report of an Initial Rapid Program Assessment (2005-2009)

Background

Abstract

AHRQ recognizes that periodic assessments of the evidence base supporting each of the comparative effectiveness reviews is an important and necessary part of the Effective Health Care Program. Such assessments can lead to the decision to update a comparative effectiveness review.

Questions

The assessment of the evidence base will include the following questions and others depending on the topic of the comparative effectiveness review. Have new medications, procedures, or devices been introduced?

  1. Have the existing medications, procedures, or devices been approved for new indications?
  2. Have any new advisories or alerts been issued?
  3. Has there been a change in scope (e.g., new patient populations, new outcomes)?
  4. Is there new evidence from new studies or studies that were incomplete at the time of the existing report?
  5. Have new methodologies been introduced (e.g., new statistical techniques or significant changes in the Comparative Effectiveness Review Methodology Guide)?

The answers to these questions will be sought through searches of the medical literature and searches of the FDA and Health Canada Web sites as well as through informal conversations with medical experts in the topic area, including members of the original report's Technical Expert Group (TEG) and the panel of peer reviewers.

At the conclusion of the review a summary table will be produced outlining the findings and recommendations will be made regarding the need for updating. Updates will be considered within the ongoing priority-setting processes of the Effective Health Care Program.